Chapter 1. Epidemiology and Background

• Global Response
• Long-term Control and Prevention
• Two Types of Cases: New and Previously Treated
• XDR-TB
• TB Epidemiology Overview
• Global Burden
  • TABLE 1: The 25 Priority MDR-TB and XDR-TB Countries, 2007-2008
• United States
  • FIGURE 1: MDR-TB in the U.S., 1993-2006
  • TABLE 2: Drug Resistance Among Foreign-Born Persons in the U.S., 2005-2006 Combined
• Development of Resistance
• Evolution and Genetic Basis
  • TABLE 3: Mutations
• Factors that Create Resistance
• Summary
• References