Chapter 7. Adverse Reactions

• Introduction
• Gastrointestinal
  • Nausea and Vomiting
  • Diarrhea
  • Hepatotoxicity
• Dermatologic and Hypersensitivity Reactions
  • TABLE 1: Suggested Drug Rechallenge Doses
  • TABLE 2: Oral Desensitivation for INH, RIF, EMB
• Hematologic Abnormalities
• Severe Drug Reactions
  • Hypersensitivity Syndrome
  • Rifampin Hypersensitivity Reactions
• Neurotoxicity
  • Peripheral Neuropathy
• Central Nervous System Toxicity
  • Depression, Psychosis, Suicidal Ideation
  • Seizures
  • Serotonin Syndrome
• Ototoxicity
• Ophthalmic Toxicity
• Nephrotoxicity
• Musculoskeletal Adverse Effects
• Miscellaneous Adverse Reactions
  • Hypothyroidism
• Summary
• References